Senior Director, Clinical Operations

About the role

1nHealth is hiring a Senior Director, Clinical Operations to lead two core functions that drive study success: Enrollment Operations (site engagement + participant pre-qualification through referral handoff) and Project Management (project delivery leadership and client execution). This leader will oversee the Manager of Enrollment Operations (who leads the Enrollment Operations teams) and two Project Delivery Leads (who manage Project Managers).

In this role, you’ll own the operational engine that converts interested participants into qualified referrals that research sites can convert into enrolled patients, and ensure studies are executed predictably for clients and sites. You’ll oversee the full lifecycle of referral engagement—from the moment a participant expresses interest through pre-qualification, referral handoff, and ongoing site coordination—while also setting the standards, rhythms, and accountability that enable our Project Management function to deliver consistently strong client outcomes.

This is a role for someone who thrives on accountability, can drive performance across moving parts, and brings clarity to complexity. You will refine systems, guide strategy, and help 1nHealth deliver a consistently excellent experience to both research sites and patients—at scale.

Duties and Responsibilities

Enrollment Operations: Strategy and execution (pre-qualification + site engagement)

• Lead the strategy and day-to-day execution of participant pre-qualification and referral-to-site workflows, from initial participant contact through handoff to the research site.
• Manage and develop the Site Coordination and Enrollment Operations teams through your Enrollment Ops leadership, including hiring input, training standards, performance management, and ongoing development.
• Build and refine processes to improve speed, accuracy, and accountability across outreach, pre-qualification, documentation, follow-ups, and site handoffs.
• Establish and track team KPIs, including outreach speed, contact rates, pre-qualification completion, referral quality, site response time, and conversion through key funnel stages (post-handoff).
• Identify blockers in the referral process (participant responsiveness, eligibility clarity, site capacity/response issues, handoff friction) and work cross-functionally to remove friction quickly.
• Guide internal understanding of how sites behave and what influences conversion across therapeutic areas, and translate insights into operating improvements.
  
  Project Management: Delivery leadership and client execution

• Lead the Project Management function through two Project Delivery Leads, setting consistent standards for how studies are executed across kickoff, ongoing delivery, risk management, and closeout.
• Establish clear expectations for client communication, internal alignment, escalation paths, and ownership of deliverables.
• Partner with Enrollment Operations and Project Management leadership to forecast operational needs, align staffing and site capacity, and ensure study goals are achievable and clearly communicated.
• Drive consistency in project hygiene (timelines, decision logs, status reporting, documentation standards) so teams and clients have a clear source of truth.
• Serve as an escalation point for key clients and ensure issues are handled quickly, professionally, and with strong internal follow-through.
  
  Business Development partnership and project handoffs

• Partner closely with Business Development to ensure smooth, consistent handoffs from signed work to execution, including clear scoping, timelines, and success criteria.
• Establish and maintain a standardized handoff process and internal kickoff expectations to reduce friction and ensure teams start projects with the information and alignment needed.
• Provide operational input into scoping and feasibility as needed to ensure commitments made during the sales process are executable.

Qualifications

• 8–12+ years experience in clinical operations, site engagement, patient recruitment operations, CRO/site operations, or related fields.
• 4+ years leading leaders (managers of teams), with demonstrated ability to scale operations and develop management capability.
• Strong experience driving performance in operational, metrics-based environments (building KPIs, running operating reviews, improving processes).
• Proven ability to manage client-facing teams and handle escalations with strong judgment and calm execution.
• Strong process orientation: able to bring structure to complex workflows and create documentation teams actually use.
• Excellent written and verbal communication; able to set clear expectations, align stakeholders, and drive outcomes in a fast-moving environment.

Travel

• Occasional travel is required for conferences, team offsites, and select client meetings.
  
  

What makes us different?

• Unlimited PTO
• 100% remote work
• Access to employee discount program
• Benefits
• 401(k) with employer contribution
• Employer-covered basic Life Insurance