Principal Statistical Programmer

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Principal Statistical Programmer in the United States.

This senior-level role sits at the core of clinical and pharmaceutical research, leading statistical programming efforts that directly support clinical trials, regulatory submissions, and real-world evidence generation. You will oversee complex programming projects, ensuring high-quality statistical outputs that inform critical drug development decisions. Acting as both a technical leader and project lead, you will coordinate cross-functional teams, manage timelines and deliverables, and ensure compliance with industry standards. The role combines deep SAS expertise with leadership responsibilities, including mentoring junior programmers and guiding methodological best practices. You will collaborate closely with statisticians, clients, and internal stakeholders to translate analysis plans into robust datasets, tables, and figures. This is a highly impactful position in a remote, collaborative environment where precision, scientific rigor, and operational excellence are essential.

Accountabilities

You will lead statistical programming projects end-to-end, ensuring accurate, timely, and compliant delivery of clinical analysis outputs while guiding teams and improving programming standards across studies.

Lead one or more statistical programming project teams to deliver analysis datasets, tables, figures, and listings on time and within quality standards
Manage project resources, timelines, budgets, and study-level metrics across multiple concurrent initiatives
Collaborate with statisticians and clients to review analysis plans and implement study-specific requirements
Develop, review, and maintain analysis dataset specifications and complex SAS programs
Produce and validate statistical outputs, including SDTM/ADaM datasets, summaries, and regulatory documentation
Prepare and package final deliverables, including DEFINE.xml, Reviewer’s Guides, and submission-ready documentation
Serve as a technical consultant and represent statistical programming in cross-functional and client meetings
Mentor junior programmers and contribute to training, process improvement, and macro library development

Requirements

You bring deep expertise in SAS programming and clinical research environments, combined with strong leadership capabilities and a solid understanding of pharmaceutical data standards and statistical methodologies.

Bachelor’s degree or equivalent in a relevant field
10+ years of SAS programming experience, including at least 7 years in the pharmaceutical or clinical research industry
Strong expertise in SAS/Base, SAS Macro programming, and ODS outputs (Word, Excel, XML)
Extensive experience with CDISC standards (SDTM, ADaM) and clinical data structures
Proven ability to develop complex SAS macros and optimize programming workflows
Solid understanding of statistical concepts and clinical analysis methodologies
Experience leading programming teams and managing multiple concurrent projects
Strong skills in technical documentation, analysis specifications, and regulatory deliverables
Excellent communication, organization, and stakeholder management abilities
Proficiency in Microsoft Word and Excel for technical and reporting purposes

Benefits

Fully remote work opportunity across the United States
Competitive salary package
401(k) with company match
Comprehensive medical, dental, and vision insurance
Health Savings Account (HSA) and Flexible Spending Account (FSA) options
Paid time off (including discretionary PTO) and paid holidays
Tuition reimbursement and career development opportunities
Employee assistance and wellness programs
Short-term and long-term disability coverage
Life insurance coverage
Telemedicine and virtual healthcare access
Adoption assistance programs
Employee discount programs
Flexible and supportive work environment focused on growth and well-being

How Jobgether works:

We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team.

We appreciate your interest and wish you the best!

Why Apply Through Jobgether?

Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time.

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Principal Statistical Programmer

Requirements

Benefits

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