<div class="content-intro"><p><span style="text-decoration: underline;"><strong><span data-contrast="auto">Mavericks Wanted</span></strong><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335559740":240}"> </span></span></p><p><span data-contrast="auto">When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on</span> <br><span data-contrast="auto"> </span> <br><span data-contrast="auto">In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. </span> <br><span data-contrast="auto"> </span> <br><span data-contrast="auto">Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.</span><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335559740":240}"> </span></p></div><h3><u>What You'll Do</u></h3><p>The Executive Director, Scientific & Medical Excellence is a senior leadership role within Medical Affairs, accountable for the cross-cutting scientific capabilities and programs that serve BridgeBio’s portfolio. This leader will own evidence generation planning, the investigator-sponsored trial (IST) and sponsored research portfolio, Medical Information, expanded access / compassionate use programs, and the integration of artificial intelligence into Medical Affairs ways of working—while driving global planning and alignment across affiliates and functions.</p><p>This individual will build and scale the operating model, governance, and standards that allow Medical Affairs to act with scientific rigor, speed, and compliance. The role requires deep expertise in rare disease, the maturity to lead in a matrixed, fast-paced environment, and the vision to modernize how a medical organization generates and exchanges scientific evidence. The role partners closely with Clinical Development, Regulatory, Commercial, Market Access, HEOR, Patient Advocacy, and Field Medical.</p><h3><u>Responsibilities</u></h3><p><strong>Evidence Generation Planning</strong></p><ul><li>Lead the development of the integrated evidence generation plan, in partnership with HEOR, aligned to overarching medical and asset strategy and informed by clearly prioritized scientific and stakeholder evidence gaps.</li></ul><ul><li>Coordinate the planning of real-world evidence (RWE), registries, natural history studies, database analyses, and Phase 4 / post-marketing studies in partnership with Clinical Development, HEOR, and Biostatistics.</li></ul><ul><li>Ensure evidence plans support regulatory interactions, value demonstration, payer engagement, and HTA requirements, and that data are disseminated through a coordinated publication strategy.</li></ul><p><strong>Investigator-Sponsored Trials (IST) & Sponsored Research Partnerships</strong></p><ul><li>Own the strategy, governance, and end-to-end operations of the investigator-sponsored trial (IST) program, including the review committee, scientific prioritization, and funding decisions aligned to medical strategy and evidence gaps.</li></ul><ul><li>Develop and manage sponsored research collaborations and external research partnerships with academic centers, consortia, and cooperative groups.</li></ul><ul><li>Establish transparent processes for proposal intake, contracting, milestone tracking, publication expectations, and compliant oversight of supported research.</li></ul><ul><li>Partner with Legal, Compliance, Finance, and Regulatory to ensure all externally sponsored research meets internal standards and applicable regulations.</li></ul><p><strong>Medical Information</strong></p><ul><li>In partnership with the Bridge Bio MI Lead, manage affiliate Medical Information function, including strategy, content, and operations for responding to unsolicited requests from healthcare professionals, patients, and other stakeholders.</li></ul><ul><li>Oversee development and scientific governance of standard response documents, FAQs, and the medical information content library, ensuring accuracy, balance, and compliance.</li></ul><ul><li>In partnership with Central Med Info, manage call center / vendor operations, escalation pathways, and service-level standards for medical inquiry handling.</li></ul><p><strong>Expanded Access / Compassionate Use Programs</strong></p><ul><li>Develop, implement, and manage expanded access / compassionate use (early access, named-patient, and managed access) programs in alignment with medical, regulatory, and ethical standards.</li></ul><ul><li>Establish governance, eligibility criteria, request-handling workflows, and supply coordination, balancing patient need with program integrity and compliance.</li></ul><ul><li>Partner with Regulatory, Clinical, Supply Chain, Legal, and Patient Advocacy across regions to ensure consistent, equitable, and compliant access processes.</li></ul><p><strong>Technology & Innovation in Medical Affairs</strong></p><ul><li>Define and drive the Medical Affairs AI strategy—identifying, piloting, and scaling AI and advanced analytics use cases across medical information, evidence synthesis, content generation, insights, and operations.</li></ul><ul><li>Partner with Data Science, IT, Legal, and Compliance to establish responsible-use, governance, validation, and data-privacy guardrails for AI tools in a regulated environment.</li></ul><ul><li>Champion change management and capability building so teams adopt new tools effectively, with measurable impact on quality, speed, and decision-making.</li></ul><p><strong>Global Medical Planning & Alignment</strong></p><ul><li>Drive global medical planning and alignment, harmonizing strategy, standards, and ways of working across affiliates, regions, and partners.</li></ul><ul><li>Build the operating model, governance forums, and shared tools/metrics that ensure consistency while enabling regional execution.</li></ul><ul><li>Serve as a connective leader across Medical Affairs sub-functions and cross-functional partners to ensure coordinated, on-strategy delivery.</li></ul><p><strong>Leadership & Compliance</strong></p><ul><li>Coach and develop a high-performing team; foster a culture of integrity, scientific rigor, and operational excellence.</li></ul><ul><li>Collaboratively develop and help execute medical plans in alignment with the company’s overall strategy.</li></ul><ul><li>Help manage relationships with key external stakeholders, including investigators, delivery systems, advocacy groups, and academic partners.</li></ul><ul><li>Represent the company at scientific conferences, advisory boards, and external forums.</li></ul><ul><li>Ensure that all medical activities are conducted in a compliant manner.</li></ul><p> </p><h3><u>Where You'll Work</u></h3><p>This is a U.S.-based remote role that will require periodic, or as-needed, visits to our San Francisco office, plus travel for conferences, partner meetings, and global alignment (approximately 20% of time).</p><p> </p><h3><u>Who You Are</u></h3><ul><li>MD, DO, PharmD, PhD, or equivalent advanced scientific or clinical degree.</li></ul><ul><li>12+ years of experience in Medical Affairs, including leadership roles, within the biopharmaceutical industry and/or academic medicine.</li></ul><ul><li>Demonstrated, hands-on leadership experience across several of the core areas of this role: Medical Information, investigator-sponsored / sponsored research programs, evidence generation planning, and expanded access / compassionate use programs.</li></ul><ul><li>Experience driving AI, digital, or advanced-analytics initiatives within Medical Affairs strongly preferred.</li></ul><ul><li>Experience leading global or multi-region medical planning and alignment in a matrixed organization.</li></ul><ul><li>Demonstrated experience in rare disease strongly preferred.</li></ul><ul><li>Strong understanding of regulatory and compliance requirements related to medical information, externally sponsored research, expanded access, and post-marketing activities.</li></ul><ul><li>Strategic thinker with strong execution capabilities and a track record of building scalable processes, governance, and teams.</li></ul><ul><li>Excellent written and verbal communication skills, including experience presenting to senior leadership and external stakeholders.</li></ul><ul><li>High degree of scientific rigor, integrity, and patient-centered focus.</li></ul><p> </p><p><span style="color: rgb(236, 240, 241);">#LI-LN1</span></p><div class="content-pay-transparency"><div class="pay-input"><div class="description"><div><div>At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.</div></div></div><div class="title">Salary</div><div class="pay-range"><span>$279,000</span><span class="divider">—</span><span>$330,000 USD</span></div></div></div><div class="content-conclusion"><p><strong>As a global company, our comprehensive benefits may vary based on location. <span data-contrast="auto">We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.</span></strong></p><p><span style="text-decoration: underline;"><strong><span data-contrast="auto">For Full-Time U.S Based Roles:</span></strong></span></p><p><strong><span data-contrast="none">Financial & Rewards </span></strong><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559738":0,"335559739":0,"335559740":240}"> </span></p><ul><li data-leveltext="" data-font="Symbol" data-listid="5" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="1" data-aria-level="1"><strong><span data-contrast="none">Market-leading compensation</span></strong><span data-contrast="none"> </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="5" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="2" data-aria-level="1"><strong><span data-contrast="none">401(k) with employer match</span></strong><span data-contrast="none"> </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="5" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="3" data-aria-level="1"><strong><span data-contrast="none">Employee Stock Purchase Program (ESPP)</span></strong><span data-contrast="none"> </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="5" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="4" data-aria-level="1"><strong><span data-contrast="none">Pre-tax commuter benefits</span></strong><span data-contrast="none"> (transit and parking) </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="5" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="5" data-aria-level="1"><strong><span data-contrast="none">Referral bonus</span></strong><span data-contrast="none"> for hired candidates </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="5" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="6" data-aria-level="1"><strong><span data-contrast="none">Subsidized lunch and parking</span></strong><span data-contrast="none"> on in-office days </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><p><strong><span data-contrast="none">Health & Well-Being </span></strong><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559738":0,"335559739":0,"335559740":240}"> </span></p><ul><li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="1" data-aria-level="1"><strong><span data-contrast="none">100% employer-paid medical, dental, and vision premiums</span></strong><span data-contrast="none"> for you </span><strong><span data-contrast="none">and</span></strong><span data-contrast="none"> your dependents </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="2" data-aria-level="1"><strong><span data-contrast="none">Health Savings Account (HSA)</span></strong><span data-contrast="none"> with annual employer contributions, plus </span><strong><span data-contrast="none">Flexible Spending Accounts (FSA)</span></strong><span data-contrast="none"> </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="3" data-aria-level="1"><strong><span data-contrast="none">Fertility & family-forming benefits</span></strong><span data-contrast="none"> </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="4" data-aria-level="1"><span data-contrast="none"> </span><strong><span data-contrast="none">Expanded mental health support</span></strong><span data-contrast="none"> (therapy and coaching resources) </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="5" data-aria-level="1"><strong><span data-contrast="none">Hybrid work model</span></strong><span data-contrast="none"> with flexibility </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="6" data-aria-level="1"><strong><span data-contrast="none">Flexible, “take-what-you-need” paid time off</span></strong><span data-contrast="none"> and company-paid holidays </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":1080,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"hybridMultilevel"}" data-aria-posinset="7" data-aria-level="1"><strong><span data-contrast="none">Comprehensive paid medical and parental leave</span></strong><span data-contrast="none"> to care for yourself and your family </span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":240}"> </span></li></ul><p><strong><span data-contrast="auto">Skill Development & Career Paths:</span></strong><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335559740":240}"> </span></p><ul><li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1"><span data-contrast="auto">People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility</span><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="2" data-aria-level="1"><span data-contrast="auto">We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching</span><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335559740":240}"> </span></li></ul><ul><li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="3" data-aria-level="1"><span data-contrast="auto">We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities</span><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335559740":240}"> </span></li></ul></div>