Director, Clinical Trial Team Lead - Oncology

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Director, Clinical Trial Team Lead – Oncology in the United States.

This leadership role sits at the intersection of clinical strategy, early development execution, and high-impact team management within oncology research. The position is responsible for guiding experienced Clinical Trial Execution Experts and Clinical Trial Leaders through the planning and delivery of early-phase oncology studies through Proof of Concept. You will play a key role in shaping operational excellence, ensuring that clinical trials are executed with scientific rigor, regulatory compliance, and strong patient-centric focus. Operating within a global and highly collaborative environment, you will partner with cross-functional teams across clinical operations, development, and enabling functions. This role requires a strong blend of strategic thinking, hands-on clinical expertise, and people leadership. It offers the opportunity to influence early clinical development strategy while building and mentoring a high-performing team driving innovation in oncology.

Accountabilities:

In this role, you will lead and develop a team responsible for early clinical trial execution while ensuring operational excellence across oncology programs through Proof of Concept. You will provide strategic direction, oversee trial delivery, and ensure alignment with scientific and development objectives.

Lead, mentor, and develop a team of Clinical Trial Execution Experts and Clinical Trial Leaders, fostering a high-performance and growth-oriented culture
Define and guide clinical execution strategies, integrating scientific, operational, and competitive insights into trial planning and delivery
Oversee end-to-end clinical trial operations including planning, execution, reporting, and risk management for early-phase oncology studies
Ensure adherence to regulatory, legal, ethical, and quality standards including GCP compliance and inspection readiness
Manage resources, budgeting, and capacity planning to support efficient and timely trial delivery
Drive cross-functional collaboration across clinical operations, study management, and enabling functions to ensure aligned execution
Lead process optimization and continuous improvement initiatives to enhance operational efficiency and innovation
Serve as a key liaison between strategy and execution teams, ensuring seamless communication and alignment across stakeholders

Requirements

This position requires deep expertise in early-phase clinical development and oncology, combined with strong leadership experience in global clinical operations. The ideal candidate brings both strategic vision and hands-on operational capability in complex clinical trial environments.

Bachelor’s degree required; advanced degree (MD, PhD, PharmD, DNP, or equivalent) strongly preferred
12+ years of experience in clinical research, including significant pharmaceutical industry experience
Extensive background in early clinical development (Phase I, First-in-Human, Proof of Concept) with a proven track record of delivering complex trials
Deep therapeutic expertise in oncology, including regulatory expectations, scientific trends, and competitive landscape understanding
Strong leadership experience managing high-performing clinical teams and developing talent in global environments
Proven experience in clinical operations including study design, CRO/vendor oversight, site management, budgeting, and regulatory compliance
Strategic and analytical mindset with the ability to translate complex scientific and operational challenges into clear execution plans
Strong communication, collaboration, and influencing skills across cross-functional and multicultural teams

Benefits

Competitive base salary ranging from $200,000 to $316,000 depending on experience and qualifications
Eligibility for discretionary annual bonus and additional compensation programs
Relocation support and other role-specific financial incentives where applicable
Comprehensive health benefits including medical, dental, and vision coverage
Retirement savings plans and financial wellness programs
Paid time off and flexible work arrangements supporting work-life balance
Opportunity to work in a global, innovation-driven oncology research environment
Leadership role with high visibility and impact on early clinical development strategy.

How Jobgether works:

We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team.

We appreciate your interest and wish you the best!

Why Apply Through Jobgether?

Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time.

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Director, Clinical Trial Team Lead - Oncology

Requirements

Benefits

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